Understanding the mechanism of action & science
Alpha-Stim® M and Alpha-Stim AID devices utilize cranial electrotherapy stimulation (CES) and microcurrent electrical therapy (MET). Learn more about the mechanism of action and science behind both technologies below.
How Alpha-Stim Works for Anxiety, Insomnia, Depression* & Pain
Cranial Electrotherapy Stimulation (CES) for anxiety, insomnia, and depression, and Microcurrent Electrical Therapy (MET) for pain.
Alpha-Stim CES is a form of non-invasive brain stimulation that applies a patented, low amplitude waveform to the brain via earclip electrodes. Psychiatric disorders, such as anxiety and insomnia, are associated with alterations in electric activity in large-scale brain networks. Research suggests that Alpha-Stim CES modulates large-scale brain network activity patterns in two synergistic ways:

Ultimately, these two ways of stimulating the brain normalize the pathological signaling in the default mode network observed in psychiatric disorders, providing rapid, effective, and lasting symptom relief without the side effects of medication.
MET is the process of directing microcurrent through the body via Smart Probes or self-adhesive AS-Trodes to treat pain. When applied peripherally, the rhythmic, low-amplitude current of Alpha-Stim MET modulates the peripheral signaling in pain circuits that emanate from the spinal cord, providing rapid, effective, and lasting pain relief with no risk of addiction or tolerance.
- Alpha-Stim M:Microcurrent is delivered via electrodes placed on the body at the pain site for the treatment of acute, chronic, and post-traumatic pain using MET. Also includes earclip electrodes for CES to treat anxiety, insomnia, and depression.
- Alpha-Stim AID:Microcurrent is transmitted to the brain via earclip electrodes using CES to treat anxiety, insomnia, and depression.*
*FDA cleared for anxiety, insomnia and pain only, with approval for depression outside of the United States.
See Alpha-Stim in Action
Watch these videos to understand exactly how the device works and how to use it.
What is Alpha-Stim
An introduction to the Alpha-Stim device and its clinically proven benefits.
How Alpha-Stim Works
Learn about the mechanism of action and science behind Alpha-Stim technology.